el alzheimer: Mal humor del enfermo de Alzheimer

el alzheimer: Mal humor del enfermo de Alzheimer

Diabetes: Balancing your insulin, medication and exercise

Controlling diabetes is a balancing act. You must carefully balance food, activity (exercise), and medications and insulin. All three are equally important to your health, and each can increase or decrease your blood glucose levels. Many of our readers ask if they need to adjust their insulin or medication before exercise.
Physical activity, or exercise, includes anything that gets you moving, such as walking, dancing or working in your garden. Staying active improves your overall health. Regular exercise helps you:

• Better control glucose levels
• Increase overall fitness
• Feel more energetic
• Improve flexibility
• Improve blood pressure
• Lower your risk of developing cardiovascular disease
• Improve your appearance, weight and overall sense of well-being

Insulin and diabetes medications lower your blood glucose. The amount of medication you need is unique to you. The time of day you take your medication and how much you take are important factors in allowing your medication to work when your blood glucose rises.
As you make exercise a part of your life, your diabetes health care provider may change or adjust your medications based on the results recorded in your diabetes record book. It's a balancing act — if you eat more than your meal plan allows, your blood glucose level may rise, or, if you exercise less than usual, your blood glucose level may rise.
Several factors affect your blood glucose during activity or exercise:

• Your physical condition
• Length of activity or exercise
• Type of activity or exercise
• Blood glucose level prior to exercising

When you're more active than usual, your blood glucose may drop too low, causing low blood glucose (hypoglycemia). It's important that you prepare ahead of time. If you're taking insulin and you know ahead of time when you will exercise, decrease your rapid or short insulin meal dose before the activity instead of taking extra food during the activity. Talk with your diabetes health care team for help making the decision about how much to decrease your insulin dose.
Also, avoid injecting insulin into your arms and legs that you will use during your activity or exercise. An abdominal injection site may help lower the risk for hypoglycemia associated with exercise.
Some additional tips:

• Test your blood glucose before, during and after the activity to monitor how it affects your blood glucose level. This is important when beginning or changing your exercise program.
• When your insulin is peaking, exercise isn't recommended, as it may lead to low blood glucose. Before you exercise, take less insulin or eat more food at mealtime or as a snack.
• If your blood glucose is less than 70 mg/dL (3.8 mmol/L), take 1 to 2 carbohydrate choices and make sure your blood glucose is in goal range before you begin the activity or exercise.
• If you were in goal range before the activity and the activity drops your blood glucose more than 30 to 50 mg/dL (1.6 to 2.7 mmol/L) or hypoglycemia occurs — blood glucose less than 70 mg/dL (3.8 mmol/L) — stop exercising and take 1 carbohydrate choice. Recheck your blood glucose after 15 minutes and repeat until your blood sugar returns to a safe range. Then, return to your exercise and take 1 carbohydrate every 30 to 60 minutes while you're active.
• Don't exercise if your blood glucose is greater than 300 mg/dL (16 mmol/L). Exercising with blood glucoses over 300 mg/dL (16 mmol/L) can raise your blood glucose even more, because exercise causes the body to release or produce extra glucose and there won't be enough insulin available to use it.
• With harder or more strenuous activity, even if you're within goal range or above goal, 2 carbohydrate choices may be necessary to prevent low blood glucose. Ask your health care provider if you have questions about this.
• For longer duration or very strenuous activities, such as downhill/cross country skiing or long bike rides, take 1 carbohydrate choice every 30 to 60 minutes during the activity. Check your blood glucose every 1 to 2 hours during the activity.
• It isn't recommended that you be active or exercise when you're sick.
• We generally don't recommend exercising before bed due to the risk of delayed post-exercise hypoglycemia. If evening exercise is necessary, consider eating an extra carbohydrate after exercise to reduce the risk of hypoglycemia while sleeping.

Remember, it's essential to check with your health care provider if you've been sedentary and want to begin an exercise routine.
Have a great week!

Stop Diabetes Naturally SHOCKING!!

Diabetes control shark antibody

Mexican scientists managed to stop some adverse effects of diabetes mellitus using antibody molecules derived from a shark living in the Sea of ​​Cortez and is popularly known as Horned Shark (Heterodontus francisci).

En la medicina contemporánea hay una corriente de investigación que trabaja con anticuerpos de diferentes especies animales como el caballo, el camello y la llama. In modern medicine there is a stream of research that works with antibodies from different animal species such as the horse, camel and llama. En México, el Centro de Investigación Científica y Educación Superior de Ensenada (CICESE) y del Laboratorio Silanes crearon una alianza para investigar los posibles usos terapéuticos de los anticuerpos de tiburón. In Mexico, the Center for Scientific Research and Higher Education of Ensenada (CICESE) Silanes Laboratory and created a partnership to investigate potential therapeutic uses of shark antibodies.

Los compuestos que se pueden obtener gracias a la técnica de anticuerpos de tiburón, son capaces de atrapar y neutralizar a algunas moléculas presentes en el cuerpo humano y que ponen en marcha procesos de inflamación y de neovascularización. The compounds obtainable through the shark antibody technique, are able to catch and neutralize some molecules present in the human body and that implement processes of inflammation and neovascularization. También se le ha reconocido a estos compuestos alguna efectividad en contra de procesos autoinmunes y tumorales, así como en la diabetes. It has also been recognized effectiveness of these compounds against some autoimmune processes and tumor as well as in diabetes.

La innovación mexicana ya fue reconocida por el gobierno de Estados Unidos, que otorgó un registro de patente para la explotación comercial de lo que describe como una nueva tecnología para elaborar fármacos. Mexican Innovation and was recognized by the U.S. government, which granted a patent registration for commercial exploitation of what he describes as a new technology to develop drugs.

Este hallazgo es único a nivel mundial y además de tener la posibilidad de generar nuevos compuestos terapéuticos útiles en el tratamiento de la diabetes, también tiene aplicaciones en el tratamiento de la artritis. This finding is unique worldwide, and besides having the ability to generate new therapeutic compounds useful in the treatment of diabetes, also has applications in the treatment of arthritis.

La patente fue otorgada después de un extenso proceso de análisis de cuatro años, que inició en noviembre de 2009, cuando Laboratorios Silanes entregó la primera aplicación provisional a la Oficina de Patentes y Marcas de Estados Unidos. The patent was granted after extensive analysis process four years, which began in November 2009 when Laboratorios Silanes delivered the first provisional application to the Patent and Trademark Office United States.

Un año antes, en 2008, la empresa recibió la exclusiva de explotación de la tecnología de los anticuerpos de tiburón, otorgada por el CICESE. A year earlier, in 2008, the company received exclusive exploitation of technology shark antibodies, awarded by the CICESE. En ese centro público de investigación fue desarrollada la nueva tecnología por un equipo encabezado por el doctor Alexei Licea. In that public research new technology was developed by a team led by Dr. Alexei Licea.

“La patente se otorgó a una tecnología ya una forma de explotación. "The patent was granted to a technology and a form of exploitation. En Laboratorios Silanes ya teníamos experiencia en el trabajo con anticuerpos de caballo, pero los anticuerpos de tiburón son moléculas mucho más pequeñas que se pueden reproducir mediante técnicas de Ingeniería Genética; son muy resistentes a las condiciones ambientales, mantienen su actividad a diferentes temperaturas, llegan rápidamente a su molécula blanco y desde el punto de vista de la tecnología para aplicaciones terapéuticas da muchas ventajas”, explicó Antonio L. At Laboratorios Silanes already had experience in working with horse antibodies, but antibodies of shark are much smaller molecules that can be played by genetic engineering techniques, are very resistant to environmental conditions, maintain their activity at different temperatures arrive quickly to its target molecule and from the point of view of the technology for therapeutic applications provides many advantages, "said Antonio L. Silanes, presidente de Grupo Silanes, que se alió con CICESE desde hace cinco años. Silanes Silanes Group president, that allied with CICESE five years.

CICESE es un centro de la red Conacyt con 40 años de experiencia en el ámbito científico nacional e internacional, ubicado en la costa de Ensenada, Baja California, en cercanía con el observatorio de la UNAM y frente a la Universidad Autónoma de Baja California. CICESE is a Conacyt network center with 40 years of experience in national and international scientific field, located off the coast of Ensenada, Baja California, in proximity to the UNAM observatory opposite the Autonomous University of Baja California.

La recién obtenida patente, da protección para la explotación comercial de la tecnología en Estados Unidos, país que representa el 50 por ciento del mercado de medicamentos en el mundo. The newly granted patent provides protection for the commercial exploitation of the technology in the United States, which represents 50 percent of the pharmaceutical market in the world. Otras solicitudes de patente se encuentran en trámite para su futura explotación en otras naciones. Other patent applications are pending for future exploitation in other nations.

Dos de los síntomas que atienden los nuevos biofármacos son la inflamación de las arterias y la neovascularización en las retinas. Two of the symptoms that serve the new biopharmaceutical are inflammation of the arteries and neovascularization in the retinas. Ambos se manifiestan en personas con diabetes y si se descuidan pueden provocar ceguera. Both are manifested in people with diabetes and if neglected can lead to blindness.

Fuente: Su médico Source: His medical

Prevention & Treatment of Diabetes

If you have a family history or other risk factors for diabetes or if you have been diagnosed with prediabetes, there are a number of healthy living tips you can follow to prevent or delay the onset of diabetes. If you have already been diagnosed with diabetes, these same tips can slow the progression of the disease.
Many studies show that lifestyle changes, such as losing weight, eating healthy and increasing physical activity can dramatically reduce the progression of type 2 diabetes and are important to controlling type 1 diabetes. These lifestyle changes can help minimize other risk factors as well, such as high blood pressure and blood cholesterol, which can have a tremendous impact on people with diabetes.
In many instances, lifestyle changes must be complemented by a regimen of medications to control blood glucose levels, high blood pressure and cholesterol as well as to prevent heart attack and stroke, which claim the lives of many diabetes patients.
By working with your health care team, you can set personal treatment goals, monitor your critical health numbers, and successfully manage diabetes while preventing complications from diabetes.

Diabetes and Stroke
A multi-part series on diabetes and stroke from Stroke Connection magazine:

Diabetes & Stroke
Understanding how to manage these co-occurring conditions.

The Diabetes & CVD Connection
We talked to Dr. Prakash Deedwania about the relationship between diabetes and cardiovascular disease.

Tips for Keeping on Track 
Diabetes requires constant monitoring, especially for those who use insulin. In addition to medication, lifestyle prescriptions must be adhered to. Helpful tips on how to manage medications and lifestyle prescriptions.

Treating Diabetes with Diet and Exercise
Many people with diabetes do not have to take insulin. We talked to endocrinologist Dr. Dan Mihailescu, Assistant Professor of Medicine and Director of the Diabetes Education Program at the University of Illinois at Chicago about controlling diabetes through diet and exercise.

Caregivers and Diabetes
Caregivers of survivors with diabetes often find themselves doing double duty as they face the reality of keeping diabetes under control for their loved ones. We talked with cardiologist Mikhail Khosiborod of Kansas City about the most important issues faced by caregivers in this challenging situation.

Type 1 Diabetes Not Controlled in Teens

Glucose control remained inadequate in a cohort of teens with type 1 diabetes, and many of these young patients already had microvascular complications, a British observational study found.
Among a group of 96 adolescents treated at multidisciplinary young adult clinics, the mean glycosylated hemoglobin (HbA1c) level was 10%, and only 9.4% had levels below the recommended 7.5%, according to Christine Eiser, PhD, of the University of Sheffield, and colleagues.
And in a subgroup who had been diagnosed with type 1 diabetes more than 7 years earlier, 46.9% showed signs of nonproliferative retinopathy, the researchers reported online in Diabetic Medicine.
A retrospective study done a decade ago found that in a group of teens and young adults, glycemic control was suboptimal, clinic visits were sporadic, and complications were common.
The U.K.'s National Institute for Health and Care Excellence has noted that young patients with type 1 diabetes have special concerns that need to be addressed, including mental health problems.
Despite this attention, and advances in treatment, technology, and delivery systems, young patients in the U.K. appeared to be faring worse than those elsewhere in Europe.
To see if that pattern of inadequate disease control persisted, Eiser's group conducted a study between November 2010 and August 2011 that included 60% female participants whose mean age was 18 years.
Depression and anxiety were measured on the Hospital Anxiety and Depression Scale, with a cutoff point of 8 or higher suggesting a clinical diagnosis, and eating disorders were assessed on the Diabetes Eating Problem Survey, with cutoff scores of 2.5 or higher.
Most participants were white and living with their parents, and three-quarters were still in school.
They had been diagnosed an average of 8 years earlier.
A total of 76% were receiving multiple injections each day, 12.5% were on twice-daily insulin, and 11.5% were using insulin pumps.
Mean HbA1c level was higher among girls and young women, at 10.4%, than among their male counterparts, whose mean level was 9.5%.
Levels were lower for those using insulin pumps (9.2%) than for those having multiple daily injections (9.9%) or taking insulin twice daily (11.2%).
Failure to keep clinic appointments was higher, at 13.7%, in those who had been treated at the center for more than 2 years than for those treated for less than a year (10.5%).
Referrals to a clinical psychologist had been made for 21.9%, and 17.9% had kept at least one appointment.
Overall, 26.6% of patients had symptoms of anxiety and 10.9% showed symptoms of depression, while 35.1% had eating disorders.
Girls had higher scores for disordered eating than boys, with average scores of 1.4 compared with 0.6.
Those who scored above the cutoff for depression had higher HbA1c levels, at 11.7%, than those scoring lower, whose mean level was 9.8% (P=0.007).
Among those who had been diagnosed more than 7 years earlier, 94.2% had had an eye exam within the previous year, 92.3% had been screened for nephropathy, and 90.4% were evaluated for hypertension.
Those levels of screening represented an improvement over rates reported in the earlier study, the researchers noted.
A total of 14.6% had an elevated albumin-to-creatinine ratio, 4.2% had microalbuminuria, and 12.8% were hypertensive.
"We have made changes to delivery of care in our clinic to meet current recommendations for transition from pediatrics, multidisciplinary clinics, and psychological support. This has been successful to the extent that some 17.9% of young people accessed psychological support," they observed.
Nonetheless, levels of HbA1c remain too high and complications are frequent.
"Improved technologies offer the potential for better control only when the considerable burden shouldered by young people in assuming responsibility for their self-care and achieving optimal glycemic control is also addressed," they concluded